. All About Chemistry: News
Showing posts with label News. Show all posts
Showing posts with label News. Show all posts

Evonik Medavox to cease production of hydrogen peroxide and sodium percarbonate in Italy

The management of Evonik Medavox S.p.A., a company belonging to Evonik Industries, has decided to shut down production of hydrogen peroxide and sodium percarbonate in Bussi sul Tirino (Italy) by the end of March 2009. The company is forced to take this step as commercially viable production in Bussi is no longer possible due to altered market conditions. Evonik will actively seek to offer employment opportunities to as many of the affected employees as possible at its other locations in Italy or elsewhere.

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Hydrogen peroxide is an oxidizing and bleaching agent used widely in the pulp and paper industry. Italian customers will be supplied in future from Evonik’s production plants in Rheinfelden (Germany), Antwerp (Belgium), and Weissenstein (Austria).

Sodium percarbonate is used primarily as a bleaching component in powdered laundry detergents. In future, Italian customers will be supplied from Evonik’s production plants in Rheinfelden (Germany) and Althofen (Austria).
http://www.chemeurope.com/news/e/96105/


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EPC Contract for an Amine Plant Signed With Aker Clean Carbon AS

On behalf of the future partnership of the European CO2 Technology Centre Mongstad (TCM), StatoilHydro has signed an engineering, procurement and construction (EPC) contract with Aker Clean Carbon AS for an amine plant at TCM. The contract has a value of approximatelyNOK 525 million.

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According to plans, TCM shall test two different technologies for capturing CO2 from two flue gas sources with respectively low and high CO2 contents. The contract with Aker Clean Carbon AS for amine technology lasts until the end of 2011. In addition, it is planned that TCM shall also test the "chilled-ammonia" CO­2-process. The TCM project is working on putting into place an equivalent contract with another contractor.

"The contract that has been signed with Aker Clean Carbon AS is an important milestone for TCM. The ambitions for TCM as a testing arena are high. Especially, there are expectations that the centre will provide various learning effects regarding technology scale-up, operational conditions, environmental consequences and the testing of sub-contractor deliverables. One of the goals of testing amines is to qualify the technology for the large-scale treatment of exhaust gases, and at the same time develop cost-efficient technologies," saysBjorn-Erik Haugan, the managing director of Gassnova, on behalf of the TCM partnership.
http://www.chemeurope.com/news/e/96466/


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Arkema announces the acquisition of American company Oxford Performance Materials

As part of its strategy to further expand in performance materials, Arkema announced the acquisition of the US company Oxford Performance Materials, Inc. (OPM), maker of polyether ketone ketone ultra-high-performance technical polymers marketed under the brandname OXPEKK®, with sales of the order of $ 2 M.

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"Arkema has had a long-standing interest in ultra-high-performance polymers that offer outstanding technical differentiation, opening up the way for major innovations for our customers ", said Thierry Le Hénaff, Arkema Chairman and CEO. " We are delighted to welcome OPM’s teams within Arkema. I firmly believe that this new activity has a huge growth potential. ”


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Norner will lead major research project on polymers based on CO2

Norner Innovation: Norner will lead major research project on polymers based on CO2
Norner Reactor Lab.
Image: Norner Innovation.
10 Feb 2009 - Norner Innovation announced that the company will lead a four years research project with a frame of about 25 million NOK to continue the development of novel plastic materials based on CO2 as a raw material including the process and production technologies. Large companies like Yara and Superfos will join in this industrial R&D project. The project will be supported by the Norwegian Research Council.

”This is a unique possibility to utilise CO2 as a raw material in polymer production and thereby turn the problematic CO2 and environmental issues. Up to 50wt% of the polymer may be CO2. We look forward to this interesting challenge and will work hard to realise this opportunity to establish new and sustainable plastic materials” says Tine Rørvik the Director of Norner.

Norner Innovation has several advanced and industrial laboratory reactors where the polymer is produced for this project with the relevant monomers and process parameters. Together with their plastics processing lab and test centre, this enables Norner to take the lead in the research of both process technology as well as material science. The development process for control of process parameters and material properties of the polymer is going on as a continuous activity in our pilot reactors. This work will now be accelerated by this new funded project.
http://www.chemeurope.com/news/e/96445/


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Euro Chlor publishes dossier on biological effects of metallic mercury exposure

Euro Chlor, representing the European Chlor-Alkali industry, has published a new title in its series of Science Dossiers: "Metallic mercury – The biological effects of long-time, low to moderate exposures”. This publication brings an analysis and synthesis of the most relevant scientific literature on the human health effects of exposure to low to moderate levels of metallic mercury vapour and represents an authoritative reference work on this matter.

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The aim of the dossier is to present current knowledge of the effects of exposure to low levels of metallic mercury vapour and to define gaps in knowledge. For the purposes of the report, a "low level” of exposure is considered to be one that gives a kidney burden.

The new Science Dossier collates the findings of more than 120 recent scientific studies on health effects of mercury, which makes it very complete. Areas such as neurotoxicology, renal effects, immunotoxicity, cardio-vascular and cerebro-vascular toxicity, mutagenicity and carcinogenicity, reproduction toxicity and finally endocrine toxicity are explored.
http://www.chemeurope.com/news/e/96406/


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Silicate performs strongly at bone regeneration

Biomaterials scientists in Taiwan have developed a quick-setting cement that could help broken bones to regenerate.

Scanning electron microscope micrograph of the silicate cement

A biocompatible layer of bone-like apatite nodules forms on the cement's surface when it is immersed in a physiological solution

Calcium phosphates were developed over 20 years ago as alternatives to polymer-based cements for mending damaged bones. Their chemical similarity to bone means that they are good repair materials and they are less toxic and more fracture-resistant than polymer cements. However, the absence of silicon - thought to be an important trace element in the early stages of bone formation - means that calcium phosphate cements are not perfect when it comes to integrating with living tissue.

By using silicate rather than phosphate, a team led by Shinn-Jyh Ding at Chung-Shan Medical University, Taichung, has developed a quick-setting cement with promising biological properties. Earlier calcium silicate formulations had setting times of over an hour, which is too long for clinical applications, says Ding, but the new cement sets in just five minutes. It should be a good candidate for bone replacements, he adds, because a biocompatible layer of bone-like apatite nodules forms on the cement's surface when it is immersed in a physiological solution. Ding says that tests in vitro suggest that the cement should encourage the growth of osteoblasts, the cells that are responsible for generating bone tissue, opening up the possibility of its use as an implant material.

"This work broadens our knowledge in this growing field, and I look forward to reading further studies by this group"
- Jake Barralet, McGill University, Montreal, Canada
Future research by the group, says Ding, will focus on improving the injectability and durability of the cement, which he suggests might be achieved by adding natural materials such as gelatin and chitosan.

Jake Barralet, a specialist in bioceramics at McGill University, Montreal, Canada, says that materials that stimulate tissue repair are the 'next big thing' in regenerative medicine. 'It is not yet clear precisely what material parameters cause cell differentiation and tissue regeneration in bone, but this work broadens our knowledge in this growing field, and I look forward to reading further studies by this group,' he says.

David Barden

http://www.rsc.org/Publishing/ChemTech/Volume/2009/03/silicate_cement.asp




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China pushes for higher quality patents

Hepeng Jia and Yue Yuan/Beijing, China

In an effort to boost the quality of patent applications, and encourage Chinese firms to obtain international patents, China has revised its patent law.

The amendment, passed by the standing committee of the National People's Congress on 27 December 2008, will take effect on 1 October 2009. It is intended to encourage independent innovation, said Chen Guangjun, director of the standing committee's science and technology office.

Former patent law revisions in 1992 and 2000 were introduced to enable China to absorb foreign technologies and to abide by international rules.

The new law adopts an international 'absolute standard for novelty' principle for patent authorisation rather than the 'relative novelty' which was previously stipulated. A patent can be approved under relative novelty if the invention or technology is new in China. But with the new 'absolute' principle, a Chinese patent can only be given to an invention or technology that is totally novel worldwide.

Meanwhile, the law now encourages Chinese citizens to obtain international patents by removing the requirement for them to apply first for a Chinese patent. Cao Man, president of new energy company Qingdao Tianren Environmental Technology, predicts that the higher patent standard will drive innovation in low carbon technologies in the long term but will have very limited short-term impact. 'We are still catching up with foreign technologies and most players in the field do not have enough innovative technologies that are ready to be patented,' Cao told Chemistry World.

And because of the high cost of applying for foreign patents, innovators have to consider multiple factors such as the market prospects in other countries before they decide to apply abroad, said Lin Xiaodong, director of Peking University Health Centre's patent management office.

Besides the above amendments, the new law revision also strengthens China's compulsory patent licensing, such as for HIV/AIDS drugs in times of a public health crisis.

http://www.rsc.org/chemistryworld/News/2009/January/26010901.asp




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Smoothing the cracks in epoxy resin

Researchers in China have developed a self-healing epoxy resin which can be repaired by heating when cracks form.

Epoxy resin is a tough polymer with many uses from glues to circuit boards, aerospace engineering to art restoration. Epoxy materials are often used under harsh conditions where long-term service and durability are needed. So, it would be ideal if damaged epoxy resin could self-heal, a property recently developed for other polymers.

cracks in cured epoxy

Gradual recovery from cracks in cured epoxy due to its remendability

Conventional epoxy resin is based on epoxides to which an additive (or curing agent) is added to form cross-linking between the chains strengthening the polymer. However, these cross-linked bonds are usually irreversible meaning that if cracks form, the bonds cannot be remade to repair the material.

Min Zhi Rong and co-workers from Zhongshan University, Guangzhou, China, have solved this problem by making a new epoxy material which contains both epoxide and furan groups in the same molecule. To this they add a maleimide-based curing agent, as well as the conventional anhydride curing agent.

The anhydride forms irreversible strong bonds with the epoxide groups but the maleimide makes bonds with the furan groups which are reversible at 110 degrees centigrade. So when cracks form in the cured polymer, it is heated to 120 degrees centigrade to break the reversible bonds and then cooled to 80 degrees centigrade so the broken bonds could reform.

'The smart epoxy not only has the superior properties over conventional epoxy', claims Rong, 'but it also exhibits thermal self-healing'. Rong goes on to say that his epoxy 'may prolong the service of the products made from the resin'.

Fred Wudl, a polymer expert from University of California, Los Angeles, US, says Rong's work 'is an interesting step towards creating remendable epoxy resins, following on from previous work in the field.'

Rong says that his group is currently working to make an epoxy resin which will be able to self-heal at lower temperatures.

Ruth Doherty

http://www.rsc.org/Publishing/ChemScience/Volume/2009/03/Smoothing_cracks.asp




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Pfizer's Wyeth injection

Pfizer has agreed to pay $68 billion (£48.3 billion) for rival US biopharmaceutical firm Wyeth, gaining access to its rich product portfolio and promising pipeline of experimental drugs. Pfizer hopes Wyeth's products will fill the financial void that cholesterol drug Lipitor (atorvastatin), which currently brings in $13 billion a year, will leave when it loses patent protection in 2011.

The merged company will boast a product portfolio that includes 17 blockbuster drugs covering a broad range of therapeutic areas, such as cardiovascular, oncology, women's health, central nervous system, and infectious disease. The news of the deal comes after weeks of speculation over who was in Pfizer's sights for a takeover, and has also put an end to Wyeth's takeover talks for Netherlands-based vaccine manufacturer Crucell.

Deals of this size are never without consequences, and in this case, Pfizer has already said it will be looking to cut 15 per cent of the combined company's workforce, as it seeks to save $4 billion from the combined company's annual costs. The extra 19,500 job losses will be on top of the 13,000 jobs the company has cut over the last two years. Even without the deal, Pfizer chief executive Jeffery Kindler said that the firm was planning to shed another 8,000 jobs by 2012.

Jeffery Kindler
Jeffery Kindler, Pfizer's CEO, explains the merger

As details of the deal were announced, it emerged that the two companies have been in talks for months. Pfizer's desire to tighten the focus of its research efforts may have played a part in Wyeth's decision in December 2008 to concentrate its drug discovery efforts in just six therapeutic areas - oncology, central nervous system, vaccines, musculoskeletal, metabolism and inflammation.

Bank raid

The cash-and-stock deal will see Wyeth shareholders receive $50.18 per share and will be financed, in part, by loans from a consortium of banks amounting to $22.5 billion - a remarkable amount considering the current reluctance of banks to lend money. The consortium includes Goldman Sachs, JPMorgan Chase, Citigroup and Bank of America, all of which were in the queue for the US Government's $125 billion bail-out package.

Pfizer's shareholders will also pitch in to fund the deal - the company halved its quarterly dividend to just 16 cents a share compared to the last quarter.

According to Kindler, 'the combination of Pfizer and Wyeth provides a powerful opportunity to transform our industry. It will produce a distinct blend of diversification, flexibility, and scale... that positions the combined company for success.'

However, analysts and commentators have questioned whether making such a big company even bigger is the correct way to go. Derek Lowe, US medicinal chemist and Chemistry World's 'In the pipeline' columnist, has taken a dim view of the merger, saying that Pfizer doesn't have a great record of making acquisitions work. 'Pfizer's own labs certainly haven't done a good job producing compounds. Some of that has been sheer bad luck, but some of it may well have been the inertia that happens in a big organisation,' says Lowe.

'I think that the company's size also affects the sorts of products they advance,' he adds. 'A $200 million per year compound does them little or no good at all, whereas a smaller company would be delighted. You end up with fewer programs than you'd think a company of Pfizer's size would have.'

Matt Wilkinson

http://www.rsc.org/chemistryworld/News/2009/January/27010901.asp




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Tethered nanocubes seek out analytes

Giving biosensors room to explore can improve their sensitivity, US scientists have found. The team used tethers to extend the speed and sensitivity of blood glucose detectors, and say they hope the same approach could improve the detection of cancer and Alzheimer's.

A team led by Timothy Fisher at Purdue University have developed a new type of biosensor coined a 'nano-tetherball biosensor' based on nanocube-shaped sensors tethered by conducting carbon nanotubes to electronic circuitry. 'We wanted to test this structure as a biosensor, and used glucose as our first test because the plentiful literature offers a good basis for comparison,' explains Fisher.

Glucose biosensor
Tethered biosensors can reach out into solution

© Jeff Goecker, Purdue University

The team built the sensor from the bottom up, starting from a porous alumina support. The team grew individual single-walled carbon nanotubes in the tiny pores of the support, and as these grew they extended out of the pores and formed a loosely interlaced network of nanotubes on the support's surface.

'Each nanotube tends to have a few defects along its length and when we electrodeposit palladium out of solution - in an electroplating-like process - the metal ions come down and find those defect sites on the nanotubes and form little clusters of metal,' explains Fisher. 'We can control the process so we form small cubes rather than clumps of metal by having a moderate rate of metal deposition.'

Biocompatible gold is then electroplated on top of the palladium coating. Finally a linker ligand is coupled to the nanocubes, followed by the glucose oxidase enzyme - an enzyme that couples to D-glucose.

The detector behaves in a standard way, measuring the glucose concentration based on the electrocatalytic detection of hydrogen peroxide produced when glucose binds to the glucose oxidase. What stands this apart from what has come before is that 'the end the sensor itself is flexibly tethered to the support as apposed to being immobilised on a surface,' explains Fisher. 'This means it can actually probe around the medium where you want to sense a target species.' As the sensor can move short distances into the medium being analysed and is somewhat mobile it has increased sensitivity and gives a faster response, he adds.

In terms of sensitivity, it is 'significantly better' than the commercially available sensors, says Fisher. But he did add that 'typical glucose sensing is for diabetes and one does not need an ultrahigh sensitivity most of the time'. This point is also echoed by Michael Strano, from the Massachusetts Institute of Technology, Cambridge, US, who says that increasing the sensitivity is 'not the scientific and engineering challenge in this field as glucose is present in blood at very high concentrations. The challenges are making such sensors biocompatible and long lived in vivo, a subject not addressed in this work.'

Looking to the future, Fisher says he may try to commercialise this sensor - but having proved the concept, he is also keen to explore the device for a wide range of other sensing systems, such as cancer and Alzheimer's, by simply changing the enzyme attached to the nanocube.

Nina Notman

http://www.rsc.org/chemistryworld/News/2009/January/27010902.asp




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Plucking proteins from single cells

As part of a £5 million initiative of the Engineering and Physical Sciences Research Council, scientists in the UK have developed a microfluidic tool to mine proteins from cells.

The system, developed by Mark Neil, Oscar Ces and their colleagues at Imperial College London, uses oil droplets to solubilise and extract proteins from targeted points on a cell's plasma membrane. The spatially selective sampling is done without solubilising the whole membrane and so doesn't destroy the cell, meaning that the scientists can follow single cells to study how protein levels vary in both space and time.

An optically trapped single droplet microtool being delivered to a cell

By trapping their microtools with laser beams (red curves) the UK team can target single cells

Ces explains that the initiative, called the Single Cell Proteomics project, is a five and a half year multidisciplinary research collaboration whose aim is to create a suite of technologies to study proteins in single cells. 'Integrating the different technologies required to undertake single cell analysis is challenging,' he says, 'and there are few combinations of researchers with the combined know-how at present.'

"The team plans to look at how changes in protein levels in the plasma membrane affect signalling pathways involved in cancer growth."
The team's droplets are called smart droplet microtools (SDMs). They consist of detergent-coated oil droplets optically trapped, or controlled, using two laser beams. The SDMs can be manipulated using a microfluidic device to enable interactions between the cells and the droplets. Ces explains that protein transfers from a cell to an SDM through interactions with the detergent. It can then be analysed, with the SDM effectively acting as a storage vessel for the protein.

Adam Woolley, an expert in microfluidic systems for bioanalysis, at Brigham Young University in Provo, US, comments: 'This work showcases a clever combination of optical trapping with microfluidic manipulation of droplets and cells. The approach looks to be especially promising for the spatially localised characterisation of cell membrane components, particularly if methods can be developed to enable quantitation of targeted compounds.'

The team now plans to develop the technology for tackling key biological questions, such as how changes in protein levels in the plasma membrane affect signalling pathways involved in cancer growth. Ces suggests that the SDMs could ultimately be used to deliver material to single cells. 'We believe the platform has a great deal of potential,' he says.

Katherine Davies

http://www.rsc.org/Publishing/Journals/cb/Volume/2009/3/plucking_proteins_from_single_cells.asp

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Water split with aluminium

Aluminium clusters' ability to split water molecules and release hydrogen is dictated by the geometric arrangement of active sites on their surface, US scientists have discovered. Many aluminium clusters will absorb water onto their surfaces, but only a few take the reaction a step further, breaking up the water molecules to produce hydrogen. Understanding this relationship might lead to design of new selective catalysts for hydrogen production, or other related applications.

Welford Castleman Jr. and his group from Penn State University make their clusters by vaporising aluminium with a laser. This aluminium plasma is than expanded into a chamber containing a lower pressure gas, which forces it to cool and form the clusters. When the team exposed these clusters to water, they noticed that some of them appeared to release molecular hydrogen.

The interesting factor in these reactions is the selectivity, as Castleman explains: 'When you take sodium and throw it into water, it looks like pretty much every atom is involved in some reaction that will produce hydrogen. In our case only certain aluminium clusters react and others don't, so what we were doing was to try and sort out these unexpected reaction mechanisms.'

Water-splitting aluminium clusters

Aluminium clusters react with water to release hydrogen

© A.C. Reber, VCU/Penn State

The team discovered that only clusters of certain sizes and geometries can perform the hydrogen-forming reaction. Previously the reactivity of these clusters was thought to depend solely on the number of electrons in the cluster, but Castleman proposes that it is actually the geometric distribution of electron density on the cluster surface that dictates whether any reaction will occur. The surface of the cluster must have one aluminium atom which can act as a Lewis base in close proximity to a second site acting as a Lewis acid. The Lewis acidic site binds the oxygen atom of a water molecule, allowing abstraction of one of the hydrogen atoms by the adjacent Lewis basic site.

If a second water molecule reacts at another pair of aluminium sites somewhere close by on the cluster surface, then the two bound hydrogen atoms can be released as molecular hydrogen. While several of the clusters studied would adsorb and react with water molecules, only clusters of 16, 17 or 18 aluminium atoms had the appropriate arrangement of active sites to allow the release of hydrogen molecules.

'We are talking about production of hydrogen on a very small scale,' Castleman stresses. 'What we are doing is laying out some fundamental mechanisms by which hydrogen can be generated, perhaps giving people some idea of how they might more effectively make hydrogen in bulk quantities.'

Charles Mims, from the University of Toronto, Canada, agrees that the work is interesting. '[Castleman has shown] clear variation of the reactivity of water with aluminium clusters as a function of the cluster size, and provided insight into which sites on the clusters provide facile activation of water.' However, he is more sceptical about the possible applications of the technology: 'This system should not be viewed as providing a lead for hydrogen generation for hydrogen energy systems, since the aluminium cluster is oxidized in the process. It must be regenerated (at an energy cost higher than that available in the product hydrogen) if it is to produce more than a few hydrogen molecules per cluster.'

Castleman agrees that it will be a challenge to sustain the hydrogen formation, since they will need to work out an effective way of regenerating the clusters by removing the hydroxide groups that end up stuck to the surface after the release of hydrogen. He explains that his group are working on the problem, and that while the technology may not be suitable for bulk production of hydrogen, it could be used to provide controlled local generation of hydrogen on demand at low levels.

Phillip Broadwith

http://www.rsc.org/chemistryworld/News/2009/January/28010901.asp

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Ultra-pure boron structure discovered

Scientists have characterised a new form of elemental boron - a notoriously hard element to synthesise in a pure form - and found that ionic bonding helps hold the structure together.

There are at least 16 known polymorphs of boron, but only three of these are thought to correspond to the pure element. Now Artem Oganov from Stony Brook University, New York, US, and colleagues have made a new structure to add to the list. Termed gamma-boron, their new form of boron is made up of two forms of boron clusters - B2pairs and B12 icosahedra - arranged in a sodium chloride type structure.

'When I first saw the structure I was very surprised,' says Oganov. B2 pairs and B12 icosahedra - clusters of twelve boron atoms arranged in a regular 20 sided polyhedron - are well known in boron chemistry, but Oganov's team found that differences in electronegativity between the two forms led to partial ionic bonding. 'It is, say, 90 per cent covalent,' says Oganov. 'But the ionic component is significant and that is something that we really didn't expect.'

Boron cluster

The gamma-boron cluster, showing the B2 (yellow) and B12 (purple) clusters

© Nature

The B2 pairs and B12 icosahedra act as anions and cations, respectively, affecting other properties of the material such as the IR spectrum and electronic bandgap. Unlike other polymorphs such as alpha- and beta-boron, gamma-boron does not become metallic at increased pressure.

The new form of boron has also shed light on the element's previously unknown phase diagram, helping to map the element's phase changes in response to pressure and temperature. 'We have found a phase which has a gigantic stability field.' Oganov told Chemistry World. Between 19 and 89 GPa the new form of boron is more stable than any other structure, and it also keeps its structure at room temperature and pressure. 'We have been able to find a key to the phase diagram of boron,' says Oganov. 'It has been really embarrassing that boron was the only element for which the phase diagram was simply unknown - now we know a little bit more about how this element works'

The team determined the structure of the new material using a computational technique that allowed them to predict the most favourable positions of the atoms from just the chemical formula.

'It's a big step in understanding the phase diagram of boron,' says Mikhail Eremets at the Max Planck Institute for Chemistry in Germany. He was also impressed by the team's ability to predict and determine such complex structures. 'It's an example of fundamental breakthrough of understanding of quite a complex system.'

Manisha Lalloo

http://www.rsc.org/chemistryworld/News/2009/January/28010902.asp


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Iron helps oceans capture more carbon

A team of international scientists studying the role of iron in the storage of carbon under the ocean have confirmed that natural iron fertilisation increases the rate of carbon capture. However, the group's measurements conflicts with previous studies - and adds to ongoing concerns over planned experiments to artificially fertilise the oceans with iron as a tool to cut carbon dioxide from the atmosphere.

Iron's role in the ocean carbon cycle is to promote the growth of phytoplankton, which remove carbon dioxide from the air through photosynthesis. Whilst most of the carbon in the resulting biomass will re-enter the atmosphere through the carbon cycle, a small amount will fall into the depths of the ocean as the plankton dies, effectively locking away that carbon for up to 300 years. The theory is that the more phytoplankton there are, the more carbon will be stored in the depths of the sea.

sediment trap
The drifting sediment trap that collects samples of sinking material while drifting at 150 m.

© R T Pollard

Artificial iron-fertilisation to promote phytoplankton growth would involve dumping huge amounts of iron in areas of the ocean deficient in this mineral but having all the other ingredients needed for a phytoplankton bloom to grow. However, the idea remains highly controversial, as the likely effectiveness of the procedure - as well as its wider environmental impact - has been questioned, because the exact relationship between iron and the amount of carbon that is removed for circulation is still unknown. In 2008 the United Nations Convention on Biological Diversity agreed to halt all but small scale coastal iron fertilisation trials over concerns about the potential environmental impact.

Just act natural

The Crozex project led by Raymond Pollard and Richard Saunders from the National Oceanography Centre in Southampton, UK, studied the seas around theCrozet islands in the Southern Ocean in an attempt to confirm exactly how iron levels affect carbon capture. 'Establishing quantitatively the relationship between iron and carbon is a really key thing to do,' says Saunders.

The water around the Crozet islands is naturally supplied with iron from the volcanic islands. 'We know unequivocally that iron comes out of these land masses, enters the surrounding ocean and fertilises plant growth,' Saunders adds.

After measuring the concentrations of total dissolved iron in the ocean, the team used a variety of techniques to measure how much carbon was exported to the ocean depths. They calculated the amount of organic carbon sinking from the surface ocean (the top 100 metres that is mixed by winds and currents) to the ocean interior using 232Th-238U ratios. 'Thorium is a naturally occurring radioactive element with a high affinity for particles, but its parent uranium has a low affinity for particles,' explains Saunders. Thorium particles attach themselves to the carbon particles, and when they sink, change the normally stable ratio of thorium to uranium. 'Because we are dealing with a radioactive element with a defined half life, we can estimate the rate of downwards flux from the surface ocean,' he says.

'Deeper in the ocean we use sediment traps that are analogous to rain gauges. They are funnels that collect the particulate matter and store them in small pots,' Saunders says. One pot is then collected each month over a year long period. The team also took sediment cores to sample deeper sediments.

The team's findings confirm that natural iron fertilisation increases the amount of carbon exported to the ocean interior by two to three fold. However, this amount was 18 times greater than those seen during a 2004 experiment where a phytoplankton bloom was induced by artificially adding iron, but 77 times smaller than that of another bloom initiated by a natural source of iron - studied by another international team led by Stephane Blain, Marseille Centre for Oceanography, France, two years ago. 'We still don't know if the numbers were different because it was a different environment or if there was something fundamentally different,' says Saunders.

But despite the lack of agreement, the figure is still significantly lower than some geoengineering estimates, adds Pollard, which has 'significant implications for proposals to mitigate the effects of climate change through purposeful addition of iron to the ocean'.

'This study gives us a much better idea of what iron fertilisation in the natural sense is doing,' says Michael Behrenfeld, an expert in marine carbon cycling and climate change at Oregon State University, US. 'But why the numbers are so different remains a big question.'

But Behrenfeld is strongly opposed to the idea of artificially spiking the ocean with iron as a way to counter climate change, adding that such a process would trigger large, unpredictable changes to the ecosystem. 'There has been a large amount of discussion in the community as to whether that is a good idea. And generally speaking it is not considered to be an effect way to combat climate change - there are much better ways, with much more predictable outcomes, of dealing with CO2.'

Nina Notman

http://www.rsc.org/chemistryworld/News/2009/January/28010903.asp


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EPA's chemical evaluation process 'high-risk'

The US government's 32-year-old law regulating chemical safety needs a complete overhaul, according to Congress' investigative arm, known as the Government Accountability Office (GAO). In a 22 January report, GAO says comprehensive reform of the Toxic Substances Control Act (TSCA) - which is administered by the US Environmental Protection Agency (EPA) - should be a top priority.

In GAO's 'High Risk' priority document - which identifies the government programmes, policies, and operations most in need of fixing - the office concludes that EPA's 'inadequate progress' in assessing toxic chemicals significantly hampers its ability to protect human health and the environment.

'The Environmental Protection Agency lacks adequate scientific information on the toxicity of many chemicals that may be found in the environment - as well as on tens of thousands of chemicals used commercially in the United States,' the report concludes. GAO also criticises EPA for failing to routinely assess the risks of the roughly 80,000 industrial chemicals that are already in use in the US.

In addition, the report says action is needed to streamline and increase the transparency of EPA's Integrated Risk Information System (IRIS), a compilation of reports on specific substances and their potential to cause human health effects. GAO notes thatsome of the chemicals most likely to cause significant health problems are among the IRIS assessments that have taken the longest to complete. EPA's assessment of dioxin, for example, has been ongoing for 18 years.

Industry concerns

The American Chemistry Council (ACC), the major trade association for US chemical companies, agrees that improving the quality of EPA's chemical risk assessments is important. 'ACC has been concerned for some time that the IRIS process was moving more slowly than desired, not only in output, but also with incorporating scientific advances in risk assessment,' the group states.

Paul Anastas, the director of Yale University's Center for Green Chemistry and Green Engineering, says an overhaul of TSCA is long overdue. 'A chemicals statue should not facilitate endless review, analysis and characterisation of problems, rather it should facilitate moving toward new classes of substances of less risk to human health and the environment,' he tells Chemistry World. 'Right now, TSCA facilitates paralysis by analysis.'

The GAO report points out that the European Union's Registration, Evaluation and Authorization of Chemicals (Reach) legislation requires companies to provide safety data and risk assessments on the chemicals they produce, but TSCA generally places the onus on EPA to obtain such data. This requirement is costly and time-consuming because it compels EPA to demonstrate that certain health or environmental risks are likely before the agency can require companies to further test their chemicals.

'Without greater attention to EPA's efforts to assess toxic chemicals, the nation lacks assurance that human health and the environment are adequately protected,' GAO warns.

Political power

The new Obama administration does appear to have the political will to rework EPA's system for assessing chemicals. Throughout his campaign, Obama repeatedly discussed the importance of protecting the public and environment from toxic substances. The agency's new administrator - chemical engineer Lisa Jackson - recently listed revising and strengthening EPA's chemical risk management as one of her top priorities.

There is also an expectation on Capitol Hill that members of the Senate Environment and Public Works Committee will use the GAO report to expedite EPA reform in areas like TSCA.

But even if the White House and new Congress actively pursue modifications to TSCA, such efforts will likely face major opposition from chemical companies that have a vested interest in avoiding extra, expensive testing.

'It isn't just one or two studies that will help define the toxicology and exposure of a chemical - it will be many,' says Larry Turner, an ecotoxicologist who worked for EPA for nearly 30 years and served in the agency's toxic substances group during that time. 'This gets very expensive for the chemical companies, and for EPA as well because this extra data has to be processed and assessed,' he adds.

For its part, EPA would not comment on the GAO recommendations. The agency did note, however, that it has a newly confirmed administrator and will review the GAO report and 'respond accordingly'.

Rebecca Trager, US correspondent for Research Day USA

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Graphene to graphane by chemical conversion

An international research team have successfully converted graphene - sheets of carbon just a single layer of atoms thick - into its hydrogenated equivalent, graphane. The scientists, from the UK, Russia, and the Netherlands, say that graphane's electronic insulating properties complement graphene's conductivity, boosting the prospects of graphene-based nanoelectronics and hydrogen-fuel technologies.

The work is the first to show that a chemical approach can be used to tailor the properties of a nano-material like graphene, in order to tune it to a particular application, says Andre Geim, part of the team at the University of Manchester. The team used a stream of hydrogen atoms to reversibly convert graphene into graphane.

graphene and graphane

Adding hydrogen converts graphene (top) into graphane

© Science

Geim and his colleague Kostya Novoselov led the researchers who discovered the first simple approach to make graphene in 2004. Graphene's layer of delocalised electrons gives it remarkable conductive properties, which has since fuelled the idea of creating superfast nano-scale transistors. But one of the biggest obstacles of using it for such applications has been to understand how to control electron flow.

One possibility previously explored by Geim and Novoselov has been to cut graphene into strips only a few nanometres wide. However, 'you can never really stop current flowing when you want to,' says Geim, because graphene lacks the necessary energy gap in its electronic structure.

But graphane offers a possible way around this problem. 'What graphane brings to the game is the possibility of chemically modifiying the structure of graphene to open a gap,' says Jorge Sofo, Professor of Physics at Penn State University, US, who hypothesised the existence of a fully hydrogenated version of graphene in 2007.

'Imagine if you were able to produce a single, transparent plane of graphane - essentially a plastic - and imagine having a magic pencil with which you can remove hydrogen so you will be drawing a channel of graphene.' Sofo says he is now working with colleagues on how to create such a 'pencil', possibly with some kind of scanning tool.

Others think graphane could have applications in new fuel technologies too. Graphane has a huge hydrogen density and Alex Savchenko, who studies graphene at the University of Exeter, believes future research should focus on exploiting this property in order to store hydrogen for hydrogen fuel technologies. Sofo, however, points out that the discovery of graphane is just one small step. 'We are speaking about little atomic flakes. Hydrogenating a little atomic flake is not creating a hydrogen storage tank.'

James Urquhart

http://www.rsc.org/chemistryworld/News/2009/January/29010902.asp




Selengkapnya...

Graphene to graphane by chemical conversion

An international research team have successfully converted graphene - sheets of carbon just a single layer of atoms thick - into its hydrogenated equivalent, graphane. The scientists, from the UK, Russia, and the Netherlands, say that graphane's electronic insulating properties complement graphene's conductivity, boosting the prospects of graphene-based nanoelectronics and hydrogen-fuel technologies.

The work is the first to show that a chemical approach can be used to tailor the properties of a nano-material like graphene, in order to tune it to a particular application, says Andre Geim, part of the team at the University of Manchester. The team used a stream of hydrogen atoms to reversibly convert graphene into graphane.

graphene and graphane

Adding hydrogen converts graphene (top) into graphane

© Science

Geim and his colleague Kostya Novoselov led the researchers who discovered the first simple approach to make graphene in 2004. Graphene's layer of delocalised electrons gives it remarkable conductive properties, which has since fuelled the idea of creating superfast nano-scale transistors. But one of the biggest obstacles of using it for such applications has been to understand how to control electron flow.

One possibility previously explored by Geim and Novoselov has been to cut graphene into strips only a few nanometres wide. However, 'you can never really stop current flowing when you want to,' says Geim, because graphene lacks the necessary energy gap in its electronic structure.

But graphane offers a possible way around this problem. 'What graphane brings to the game is the possibility of chemically modifiying the structure of graphene to open a gap,' says Jorge Sofo, Professor of Physics at Penn State University, US, who hypothesised the existence of a fully hydrogenated version of graphene in 2007.

'Imagine if you were able to produce a single, transparent plane of graphane - essentially a plastic - and imagine having a magic pencil with which you can remove hydrogen so you will be drawing a channel of graphene.' Sofo says he is now working with colleagues on how to create such a 'pencil', possibly with some kind of scanning tool.

Others think graphane could have applications in new fuel technologies too. Graphane has a huge hydrogen density and Alex Savchenko, who studies graphene at the University of Exeter, believes future research should focus on exploiting this property in order to store hydrogen for hydrogen fuel technologies. Sofo, however, points out that the discovery of graphane is just one small step. 'We are speaking about little atomic flakes. Hydrogenating a little atomic flake is not creating a hydrogen storage tank.'

James Urquhart

http://www.rsc.org/chemistryworld/News/2009/January/29010902.asp




Selengkapnya...

Making magnetic monopoles, and other exotica, in the lab

February 5th, 2009 By Lauren Schenkman in Physics / Physics
Making magnetic monopoles, and other exotica, in the lab

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Physicist Shou-Cheng Zhang. Photo: Lauren Schenkman

Physicist Shou-Cheng Zhang has proposed a way to physically realize the magnetic monopole. In a paper published online in the January 29 issue of Science Express, Zhang and post-doctoral collaborator Xiao-Liang Qi predict the existence of a real-world material that acts as a magic mirror, in which the never-before-observed monopole appears as the image of an ordinary electron. If his prediction is confirmed by experiments, this could mean the opening of condensed matter as a new venue for observing the exotica of high-energy physics.


Zhang is a condensed-matter theorist at the Stanford Institute for Materials and Energy Science (SIMES), a joint institute of SLAC National Accelerator Laboratory and Stanford University. He studies solids that exhibit unusual electromagnetic and quantum behaviors, with an eye towards their use in information storage. But due to his training as a particle physicist, Zhang always keeps the big picture in mind. That’s why it was so easy for him to see that the material he was already working on could behave like what theorists call a magnetic monopole, an isolated north or south magnetic pole.

The monopole is thought of as electric charge’s magnetic cousin, but unlike positive or negative charges, north or south poles always occur together in what’s called a dipole. A lone north or south pole simply doesn’t show up in the real world. Even if you take a bar magnet and cut it in half down the middle, you won’t get a separate north and south pole, but two new dipole magnets instead. For symmetry-minded theorists, however, it’s natural that there should be a magnetic equivalent of charge. String theories and grand unified theories rely on its existence, and its absence undermines the mathematical feng-shui of the otherwise elegant Maxwell’s equations that govern the behavior of electricity and magnetism. What’s more, the existence of a magnetic monopole would explain another mystery of physics: why charge is quantized; that is, why it only seems to come in tidy packets of about 1.602×10-19 coulombs, the charge of an electron or proton.


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For decades, scientists have kept their eyes peeled for the elusive monopole, but perhaps they were looking in the wrong place. “They were literally hoping it would fall from sky,” Zhang says. The notion isn’t as far-fetched as it seems—our world is constantly bombarded by weird particles showering from far-off cosmic events, and magnetic monopoles could very well show up as part of that rain. Some enterprising physicists installed loops of superconducting material on their rooftops. If anything remotely like a magnetic monopole fell through, the loops, being sensitive to magnetic fluctuations, would register it.

But in more than 30 years of searching, no one’s been able to conclusively detect this particle. Accelerator experiments have been no more successful, leading scientists believe existing monopoles must be far too heavy to create in even the Large Hadron Collider.

Interestingly, Zhang’s magnetic monopole didn’t fall from the heavens; instead, it was leading a quiet life on the other side of a mirror, but a mirror made of a very special type of alloy. What’s more, says Zhang, the math to prove the effect is very clear. “You could give the last part of the mathematical derivation as a final exam in a junior or senior year undergraduate physics class.”

To understand how a material can act like a magnetic monopole, it helps to examine first how an ordinary metal acts when a charge—an electron, say—is brought close to the surface. Because like charges repel, the electrons at the surface retreat to the interior, leaving the previously neutral surface positively charged. The resulting electric field looks exactly like that of a particle with positive charge the same distance below the surface—it’s the positive mirror image of the electron. In fact, from an observer’s point of view, it’s impossible to tell the difference.

The concept of an image charge is something undergraduate physics students encounter in their very first electricity and magnetism class, along with the idea that the magnetic monopole doesn’t exist. But Zhang’s “mirror” alloy is no ordinary material. It’s what’s called a topological insulator, a strange breed of solid Zhang specializes in, in which “the laws of electrodynamics are dramatically altered,” he says. In fact, if an electron was brought close to the surface of a topological insulator, Zhang’s paper demonstrates, something truly eerie would happen. Instead of an ordinary positive charge, Zhang says, “You would get what looks like a magnetic monopole in the ‘mirror.’”

To go back to the example of image charges, it’s important to emphasize that there isn’t actually half of a bar magnet somewhere inside this material. Instead, Zhang discovered, due to a peculiarity of the material called strong spin-orbit coupling, the nearby electron would induce a current in the surface that circulates constantly without dying out. This in turn—undergraduate physics majors, get out your pencils—would create a magnetic field that looks like that of a magnetic monopole. Experimentalists have tried to approximate this field before, for instance by arranging permanent magnets in certain ways. But to an outside observer, Zhang’s material would be completely indistinguishable from the monopole particle that physicists were hoping to catch in their superconducting detectors.

“We like to find things that don’t exist,” says Zhang. His work on the monopole has further ramifications; this could be a way to physically realize a number of particles that, until now, have only existed as mathematical loopholes in high-energy physics theories. For instance, Zhang has shown that the electron and image monopole together would act like a so-called “anyon” located at the solid’s surface. “The ‘any,’ in this case, is as in ‘anything,’” Zhang explains—they are particles that only exist in two dimensions, whose properties straddle those of the two classes of three-dimensional particles, fermions and bosons.

Although Zhang works as a theorist, he has close ties to experimental physics. In 2007, his prediction of the quantum spin Hall effect in mercury telluride was confirmed experimentally, earning his work praise in Science as a runner-up breakthrough of that year. “As a theorist you’re always motivated by the math, but it’s a testament to our understanding that we can predict real-world materials,” Zhang says. “Before, new materials were more or less found by accident.” Now other SIMES researchers will be using the Stanford Synchrotron Radiation Lightsource at SLAC to closely study two specific materials, bismuth selenide and bismuth telluride, that Zhang has predicted will exhibit this strange mirror behavior. They hope to confirm the prediction experimentally some time this year.

“Exotic particles such as the magnetic monopole, dyon, anyon, and the axion have played fundamental roles in our theoretical understanding of quantum physics,” Zhang writes in the paper. “Experimental observation of these exotic particles in table-top condensed matter systems could finally reveal their deep mysteries.” Topological insulators could provide a new experimental outlet for high-energy physicists. “You don’t have to look towards the cosmos,” Zhang says. “I think we’ll see more of the beautiful mathematical structures of high-energy physics become realized in condensed matter physics.”

Provided by SLAC National Accelerator Laboratory, By Lauren Schenkman
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Cracking cryptic clues to the plague

Scientists in the US are modelling the behaviour of the bacteria responsible for bubonic plague to find alternative ways to target the disease. Using a novel approach called CryptFind, Eivind Almaas and Ali Navid from the Lawrence Livermore National Laboratory, US, have found the genes that the bacteria, Yersinia pestis, call upon to survive.

A flea and Yersinia pestis

Plague circulates mainly among animals, via fleas

Although the plague is widely considered to be a disease of the past - it has killed 200 million people throughout human history - it still affects thousands of people worldwide. Whilst it can usually be treated using antibiotics, several antibiotic resistant strains have recently been discovered, indicating that new treatments for the plague are needed.

But it is very difficult to study plague behaviour experimentally because of fears over public safety and the need for high-security laboratory conditions (Yersinia pestis, the bacterial cause of the disease, is classed as a potential bioterrorism pathogen by US authorities). Therefore, theoretical models, such as those developed by Almaas and Navid, are used in place of clinical studies.

"By identifying candidate cryptic genes, it is possible to target not only the primary pathway to a compound, but also eliminate dormant alternate pathways."
The US researchers used CryptFind to identify Y. pestis' cryptic genes. These genes are not normally required for cell function, but can ensure cell survival under extreme conditions. Almaas explains that it is Y. pestis' ability to initiate cryptic genes that enables it to survive in hospital environments, and complicates the development of drugs for the plague. 'By identifying candidate cryptic genes,' he says, 'it is possible to target not only the primary pathway to a compound [essential for Y. pestis survival], but also eliminate dormant alternate pathways.'

Bernard Palsson, an expert in mathematical genome modelling from the University of California, San Diego, US, says that 'it is wonderful to see more reconstructions of human pathogens appearing. Hopefully, such reconstructions will open up new dimensions in the fight against infectious disease.'

Almaas is now in the process of modelling other Yersinia variants, including Yersinia pseudotuberculosis, a precursor to Y. pestis which causes tuberculosis-like symptoms in humans.

Hilary Burch

http://www.rsc.org/Publishing/Journals/cb/Volume/2009/3/cracking_cryptic_clues_to_the_plague.asp




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Cracking a controversial solid state mystery

February 6th, 2009 in Physics / Physics

(PhysOrg.com) -- Scientists can easily explain the structural order that makes steel and aluminium out of molten metal. And they have discovered the molecular changes that take place as water turns to ice. But, despite the fact that glass blowers have been plying their trade since the first century BC, we have only just begun to understand what makes molten glass solid.

One hundred and fifty years after the construction of Crystal Palace at the Great Exhibition, scientists at The University of Nottingham and the University of California, Berkeley in collaboration with the University of Bath, have presented an explanation of how atoms behave as glass cools and hardens. Their research has just been published online in Science Express, in advance of publication in Science.

The secret of glass making came to Britain with the Romans in 55 BC. But only now do scientists believe they are a step closer to unravelling the controversy that surrounds the question: what makes solid glass different from the molten liquid from which it is formed?

Juan Garrahan, Professor of Physics, in the School of Physics and Astronomy at Nottingham said: "Snapshots taken with x-rays show that in ice, water molecules fit together in an ordered array, which is called a crystal, while in liquid water, the molecules are jumbled. Scientists can understand why ice is rigid and liquid water is fluid largely from these structural differences. Glass, on the other hand, does not offer this explanation because a snapshot of the molecular structure of solid glass is almost indistinguishable from that of the molten liquid. Both appear to be jumbled random collections of atoms. This observation is at the heart of the problem: if the solid state of glass has a molecular structure just like that of the liquid, how can it be so rigid? Controversy has resulted from the absence of a clear answer to this question."

Using computer simulations, researchers were able to test the theoretical and computational process of melting and hardening glass. They have not yet solved the glass transition problem however they have provided evidence for a new perspective on glassy phenomena which may eventually lead to its solution.

Dr. Robert Jack, from the Department of Physics at the University of Bath, said: "By focusing on the ability or inability of molecules to flow we have provided evidence for a new kind of sudden transition between the flowing liquid and the solid glass. This transformation is apparent only when the system is viewed in both space and time."

Ultimately, the answer is important because the principles that underlie the glass transition can guide scientists and engineers towards methods for producing better glass — stronger and longer lasting. Disordered glassy solids are ubiquitous in everyday materials including ceramics and plastics. For over a century, principles of thermodynamics have aided the design of ordered solids, materials like steel and aluminium alloys. No such principles are yet settled for production of glassy solids. The current work is believed to be a significant step towards these principles.

Provided by University of Nottingham

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